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Articles on this Page
- 01/01/13--00:00: _Stakeholder Salienc...
- 11/01/14--00:00: _Genotyping common F...
- 01/01/15--00:00: _Open Innovation Con...
- 01/01/15--00:00: _Electronic Government
- 01/01/16--00:00: _Electronic Government
- 01/01/17--00:00: _Time to Refuel the ...
- 01/01/17--00:00: _Electronic Government
- 01/01/15--00:00: Electronic Government
- 01/01/16--00:00: Electronic Government
- 01/01/17--00:00: Electronic Government
In this article we discuss in what ways an e-government project can give both expected and unexpected effects for agency employees and their working tasks. The purpose of this article is to illustrate the fact that, besides the aim to increase agency efficiency and citizen benefit, e-government implementation might also change the salience of involved stakeholders. We do this by focusing on one stakeholder group which was reluctant and hesitating in the beginning of the studied project; marginalized, passive, easily convinced, and old-fashioned. After the e-government implementation, this group had turned to satisfied, proud, influential, active, powerful, and modern IT users. The case shows how stakeholder salience might change over time in an e-government project. Stakeholder influence aspects and IT driven change aspects are intertwined. This makes it necessary for any e-government project to address the notion of stakeholder involvement in decision-making during the development and implementation phases, but also to acknowledge e-services force to change how things and people are perceived during these phases.
To provide an improved platform for simple, reliable, and cost-effective genotyping.
Modern fertility treatments are becoming increasingly individualized in an attempt to optimise the follicular response and reproductive outcome, following controlled ovarian stimulation. As the field of pharmacogenetics evolve, genetic biomarkers such as polymorphisms of the follicle stimulating hormone receptor (FSHR) may be included as a predictive tool for individualized fertility treatment. However, the currently available genotyping methods are expensive, time-consuming or have a limited analytical sensitivity. Here, we present a novel version of “competitive amplification of differentially melting amplicons” (CADMA), providing an improved platform for simple, reliable, and cost-effective genotyping.
Two CADMA based assays were designed for the two common polymorphisms of the FSHR gene: rs6165 (c.919A > G, p. Thr307Ala, FSHR 307) and rs6166 (c.2039A > G, p. Asn680Ser, FSHR 680). To evaluate the reliability of the new CADMA-based assays, the genotyping results were compared with two conventional PCR based genotyping methods; allele-specific PCR (AS-PCR) and Sanger sequencing.
The genotype frequencies for both polymorphisms were 35 % (TT), 42 % (CT), and 23 % (CC), respectively. A 100 % accordance was observed between the CADMA-based genotyping results and sequencing results, whereas 5 discrepancies were observed between the AS-PCR results and the CADMA-based genotyping results. Comparing the CADMA-based assays to (AS-PCR) and Sanger sequencing, the CADMA based assays showed an improved analytical sensitivity and a wider applicability.
The new assays provide a reliable, fast and user-friendly genotyping method facilitating a wider implication in clinical practise.
Working with innovation is important in several sectors and industries. One emerging arena for innovation is the arrangements of innovation contests. The aim of the paper is to describe and characterize an open innovation contest for improving healthcare, and to address the challenges involved. The research is a qualitative, explorative and interpretive case study of a Swedish region providing publicly funded healthcare. The conclusions show the need to generate and analyze data from actors with several perspectives in the contest. Challenges identified include defining and precisely expressing the problem, separating and delimiting the different problems and achieving a joint view. Other challenges were identifying and attracting knowledgeable participants, to consider incentives, and communicating the contest. In the collaboration stage, challenges involved the contest design, enabling knowledge sharing, managing various agendas, and being open-minded to new ideas; and finally, assessing whether the problem is suitable for open innovation contests at all.
There are various models and frameworks describing the nature of e-services in the public sector. Many of these models are based on previous conceptualizations and have evolved over time, but are first and foremost conceptual creations with weak empirical grounding. In the meantime, practitioners in the field have continued to further develop e-services, and new advancements in technology have enabled new solutions for e-services. In the light of advancements in practice, and the limitations seen in current conceptual work concerning public e-services, we identify a need to refuel the conceptual discussion on e-services in the public sector by empirically investigating how e-services can be manifested in practice. The aim of this paper is to illustrate the possible variations of e-services in practice, and to discuss this variation in relation to the conceptual representation of the phenomenon. Based on qualitative interviews with employees involved with e-service development and provision at a large governmental agency, we illustrate that an ‘e-service’ can take on many different forms within an organization; ranging from downloadable forms, to complicated self-service systems that require expertise knowledge and IT-systems with specific processing capacity. The notion that all services mediated through a website can be understood under one general umbrella term, without further categorization, needs to be challenged.